Peptide Potions & Pillars: What Women Need to Know
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Monday. It's been a Monday for you. It's just another manic Monday. What? You would have manic Mondays, I imagine. do. I love often that my manic Monday gets to end with something that is less manic and that's a conversation thing. Strength renewed is actually really renewing for me at the end of a manic Monday. Which is great.
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It calms your central nervous system down. It calms my central nervous system. tell you, everybody should have a strength, sources of strength renewal and a Mickey in their life and you will be happier. Well, I'm super interested to dive into what you came to the sort of table with this evening with our conversation because it isn't something that is as well
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accessed maybe, it's not in my, like I have a lot in my feed about health and wellness. And I notice in my feed from sort of people in the States and particularly your neck of the woods, there's a, and in the podcast I listened to, there's a lot on peptides. And you've been noticing it more and more in your information as well. Peptides for health essentially and targeting women of our age group. think that women are definitely getting targeted between the ages of
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you know, 30 to like 50s. And I was telling you earlier that, you know, maybe a couple of years ago, and perhaps it's just these, some of these like, you know, places that kind of offer this whole all in one package of peptides are now either, you know, I'm just getting more of them in my feed or something. But I definitely didn't feel like a couple years ago, I was like going to the like,
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grocery store of peptides. You know what mean? like didn't, it even on my radar. And that was only, you know, maybe even a year ago, really. Like I feel like in the last year, there's just so much emphasis on peptides and probably, you know, the most common one is GLPs, which are a form of a peptide. But I feel, and tell me if I'm wrong here, but I feel like there's sort of two categories in which you would think.
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as a woman that you would need to take peptides and that would be either for weight loss and hormones. is there other times in which you might be taking peptides? And then if so, when do I even know that I would need a peptide? Do I even want a peptide? Such a great question. as you said, peptides- propaganda is what it feels like. Yeah.
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So there's short chains of amino acids, just in case people don't know what a peptide is, like a little mini protein, if you like. And what they do is they act as signaling molecules in the body. So they turn on or off certain biological processes. They mimic hormones or growth factors. And this is where I feel GLP-1 sort of probably sits in that space as well. And they can also improve communication between cells. you know, we already make a lot of peptides naturally.
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insulin, GLP-1, oxytocin, but scientists, they're or synthesizing peptides that target very specific pathways for health, repair, and performance. And in a lot of cases, they are synthesizing these peptides in amounts that are much more than we would naturally produce ourselves. And they are elevated in our body if you take them for much longer than what we'd naturally have sort of available.
04:02
You mentioned, what would we even take them for? So typically, it's, as you said, hormones. So when hormones decline. Or you mentioned weight loss, so when our metabolism changes. But also when our recovery slows as well. And probably, personally, the first time I started being aware of hormones, thinking about, or sorry, thinking about peptides in the space, was listening to people talk about one called B-SPACE.
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called BPC157. And this was a really well-known peptide used for helping accelerate recovery from injuries. And a lot of people were using it in that space. But there are a range of ones. And to your point, fat loss and metabolism, you've got your GLP-1 agonists, like semiglutide, lyriglutide, and many more as well.
05:01
I just, there's a lot of these like kind of companies like Midy or Joy Women's Wellness or whatever. And they're like kind of sending you, hey, like we'll do some labs real quick and some diagnostic, you know, tests on you. And then we'll kind of outfit you essentially with your like ready to go box of, you know, peptide potions.
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I'm I'm having a little fun with this tonight, but that's kind of how it feels. I'm actually in all honesty, I feel a little bit susceptible to some of this marketing myself. so what Mickey and I are always wanting to try to do is just to like take the information and disseminate it. Kind of like open it up and look at it and then so that you all can kind of see what's inside there too. that's what I've these kinds of places and then they do that. And then what am I supposed to do? Then I just like start taking my like,
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you know, peptide potions, and then I just sail off into the kind of sunset. I just, I'm not, I just don't really quite understand this, what this all is, you know? Yeah. And it's just such a great question. Like what is the use case? mean, we've already sort of laid it out as to why people would be interested or maybe be lured into this idea that these are a bit of a panacea, but it's like anything, isn't it? Like nothing by itself is going to, um,
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is going to affect lasting and sustainable change. Like I suppose, if for example, you have some challenges with, I don't know, like neurotransmitters or you're experiencing hormone challenges that aren't related to fat loss and maybe there are peptides which actually can assist with hormonal support like Kisptin-10 or there's one called Tezimorylin.
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Maybe these are short term things to put in, like someone might take an aspirin or someone might take some, I don't know, I'm gonna say antibiotic and I know that not many people love antibiotics, do I, but I mean, they're there for a reason, know, short term use. But then to support you through a particular time to then naturally sort of come off it. But I guess what I'm hearing from you is like, there's no, you can't see a map of how we might use these things and
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in a way that supports health, but then allows you to sort of like just transition back to life without peptides. Well, that's completely the answer right there. is, or that's, sorry, that's the question. And so, and all I'm really hearing is this could potentially be, you know, well, I already know that it's probably a quick fix to weight loss. I'm certain that it'll help with weight loss, maybe in some, in a lot of cases.
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And then, you I don't know what it will do to regulate hormones. think, you know, I don't know that answer either. But I think exactly what you said, you know, if there was a road, a bit more of a roadmap right now, it just feels like unclear. You know what I mean? And I'm not sure how much of these things are like covered by insurance. They say they are, but then typically they're not. So then these are like just out of pocket, potion peptides that
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are approved, they're not illegal, but I'm like, we're taking them and then we're feeling some relief. But then, but then what happens if, if the box is laid or you're off of it for a month or something happens with your insurance or it's only covered partial and, then you have to go off that like, I just, so then what, you know, and I guess it's
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I just feel like it's unclear and the roadmap feels like there isn't one. And so I guess in some ways I'm hoping we can create, we can have this conversation or maybe there is a roadmap that we can help design for people or maybe the plan is something a little over on this side. Maybe it's not the pre-packaged thing. It's maybe looking at it this way. Well, it's, know, when you look at some of the critiques around stuff like this, it's...
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I mean, often what you hear, and I would say this is true, was interesting. Like most people, most women of our age, like we sort of want some simple solutions. Like we don't want this added complexity. But we do what, and really what we do need dialed in is that foundational stuff, the sleep, the strength training, protein, management. But if you don't have that dialed in, then the peptide,
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are likely not to provide any meaningful long lasting results, right? So definitely, I think that's huge. case scenario is if you're using these, you want to use them on top of an already strong foundational support because you might notice, and this is the reality too, is that you might actually be doing everything and still not seeing the results that you're after. So this is where the peptides can be super helpful.
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Just so you know, for a lot of people, they are high cost. So like you said, insurance may cover them, but if not, you may well be paying upwards of $600 a month. For sure. And interestingly, if you look at the research, there's not a lot of research in women, actually. there is a lot more, like peptide studies have been done in men rather than women. Short term studies,
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And potentially they're just, they're based on, and a lot of researchers like this, which is great, it's based on those short term outcomes like weight loss, but it doesn't look at sustainable weight loss. I mean, there are a few trials now with GLP-1, there are, and there is certainly trials to show that a lot of people do regain weight. But as I understand it, like if you account for some of those foundational habits, then actually they're a really helpful tool.
11:08
But I think we're just, it's in its infancy with regards to being studied in the realm of the perimenopausal menopausal woman, basically. And this is probably what we really would like is, you know, people might be getting their box of peptides, but we're not sure of, you know, long-term outcomes and what that might look like. And are you just not delaying the inevitable, but, know,
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Is there another more meaningful way you can spend your money? Do you need to put that $600 a month to a personal trainer or change up your diet so you're buying a higher quality type of food or a better bed so you get better sleep? don't know. Things like that. But I love that you always bring it back. You've been doing this and studying this for so long. And I love that you kind of look at that. But then you always go back to these...
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pillars, these sort of like really, you know, people say like, you know, the basics never die. And I don't think that they do. You know what I mean? I think you just have to, they have to be there. Like the pillars have to be really hardwired in. The strength work has to be hardwired in because, know, what we do know, certainly on the, the GLPs, on the weight loss peptides, we could, I don't really understand the other versions of these peptides. I know you mentioned a couple, but for the weight loss peptides,
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you do tend to eat less because you just, for a lot of reasons, sometimes some of the side effects is it just feels funny in your body. your digestion is slowing down a little bit and so you just can't eat the same, your appetite's there, but you just are eating so much less. So, you know, I always worry for my clients that are on them that they're just not going to get enough, like,
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nourishing like foods, right? They're not going to eat enough protein, certainly, of course, you know, but they're just not going to get enough into like of the dietary requirements. And they're off and then I think like energetically that just kind of plays into like, well, you have that in the energy to like focus on strength training while you're doing it. And I think you can certainly, but I think it's important to like recognize that you kind of need to do that because at some point you'll either be in a maintenance version of this or you might be off of
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this. you know, and same thing, I guess, you know, the hormones, I don't even know what peptides you would take. I mean, I guess that would just be like estrogen and testosterone and progesterone or is there another peptide that's supposed to help with hormones? Well, there are different peptides such as the KISS Peptin 10 that I mentioned that can assist with like hormone support. There's something else called Tezomerylin, which is like growth hormone releasing a hormone analog.
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So there are, and then also you've got ones which help with cognitive functions, so neuropeptides for anxiety and focus, which is something else that, particularly as you go through perimenopause and things like that, can get an uptick in your, you can get a, a down regulation, but GABA is our calming hormone in our brain. And there may be a change in that GABA, in the amount of GABA to glutamate ratio. And glutamate is a neurotransmitter, which is
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sort of sparks anxiety and things like that. But also progesterone really helps. so if you, so one of the key hormones for women in perimenopause is to chat to their doctor about progesterone. Because aside from all of, for any other reason, it can be really sort of calming for the brain. But you know, what I think is super important is regardless of whether people take, if they do take GLP-1 type either
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peptides or actual like Asympic or the other weight loss drugs that they'd get through their doctor and not through these clinics like the Joy Wellness Clinic or Women's Wellness Clinic or whatever is that you can't just wait until you finish taking them in order to put these lifestyle habits in place because lifestyle habits is all about reps. You just got to get those reps on the board. And the sooner you start getting those reps on the board with regards to
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figuring out ways to get in protein, even if your appetite is suppressed or doing strength training, even if you don't want to, the more you do it, the more you change the body composition in your brain. I think it's super important to just like in least complicated way. I think the reason we stress the importance of muscle on your body, and just very clinically mixed, what are like,
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why it is truly like life saving for you to have muscle. Like this is way more than aesthetics. And we're talking about like you potentially lose muscle when you're on certain weight loss peptides. It's a fact for just the two reasons that we just said, but it is so critical to have muscle. It is so life saving. If you were to say like, know, the major reasons why, what would they be?
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And so first, so my two avenues, one would be metabolic health, because when you have more muscle, you've got more of a reservoir for glucose to be disposed in. So you're protecting your body from the from having elevated blood sugars, which leads to mitochondrial damage and vascular damage and cardiovascular disease and a whole host of those things. But the other primary option
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reason would be because muscle and bone are so intricately tied and we need to be strong and resilient as we age to prevent us from breaking bones and preventing that sort of like lack of function and just lack of activity that can come when you don't have muscle. And when you don't have muscle, as you age, you run the risk of increasing fall, the likelihood of a fall and
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you're just going to further exacerbate that. So I think it's down to metabolic health and just ensuring if you're functional and you can remain as independent and resilient as possible. Metabolic, when we say metabolic health, does that, I mean, I always think like easiest way I always describe it as like, it just helps like your, your, your organs and your digestive system is just run more efficiently. Is there another way like you, when you're thinking about metabolic health, that you would just like describe it to somebody?
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Yeah, I do. Metabolic health is basically the foundation of all health. because elevated blood sugar is toxic to the body and over a long period of time, you are accelerating aging, DNA damage, you are impacting on levels of inflammation, you're changing your hormone response, you are turning fat cells into sort of more inflammatory sort of fat cells because
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they get glycated, just means that they, glucose attaches to other tissues. I don't haven't said that properly, but that's essentially what it is. Yeah, and you get damaged proteins. And so all of this stuff actually leads to disease. What did you say was toxic to the body? Blood sugar, sugar, elevated blood sugar. So muscle actually helps regulate
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Yeah, muscle is a reservoir, that's where we store carbohydrate and glucose. And so if you have a low muscle mass, regardless of your size, if you carry excess body weight or not, there's nowhere for that glucose to go. So it just stays in your bloodstream. And then that impacts on how your body is able to use energy. It impacts on how your brain functions. just impacts on so much.
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I mean, I always love to like, it was so clear to me when you're describing it, but it's literally like, it is like the little shock, the system that the muscles, the system that just kind of regulates the blood sugar. it's almost like the, you know I mean? Like the stop and the start, like no only this can come in and that can go out. And that's so critical because otherwise like the flood gates would just be open and then you would, get like an absolute excess of, you know, toxic, you know, blood sugar.
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Which is terrible for the body. It's the same thing. I understand the concept always, always described like, know, the muscle protects the bone. It's like a jacket when it's cold outside. Yeah. 100%. And I think that the more that people think about muscle mass as it relates to metabolic health, just the more they might be able to understand if they're sort of struggling to really understand why it's important to not delay.
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building muscle and trying to keep muscle. It's just so important for overall metabolic health. It's much more than just physique and what you lift in the gym. It's so much more than that. I mean, you and I will forever be reiterating that and stressing it because I do think that people think about it and still the first thing they think about is aesthetics. You know I mean? Like, great. So I have some more definition. That's awesome. What do you do? But actually, I really don't think they understand that. And in fact, it was just nice for me to even hear it again tonight.
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like blood sugar can be toxic in the body, toxic, it will kill you. you need, the muscle helps to regulate that. That is a really important point, it's nothing else. And then that's also gonna like affect weight gain too, friends. So, you know, think of it as like, it really is sort of that part of your body that helps us regulation, you know, and protection. So it's like, on one hand, it's a regulator and on the other hand, it's a protector. 100%.
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I will continue on with these kind of peptide potion discussions, but I think we'll continue to kind of unpack them because I still think people are going to want to go to them. It seems really cute. They'll get like a delivery box of all of these things, but I still think it's important to work on one thing at a time. I think getting a box.
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of too many things at one time won't allow you to understand what's actually happening in your body. Like I really think you have to look at each thing. have to look at why you're weight loss resistant. You have to look at why potentially what your side effects are that you might need an adjustment of testosterone or estrogen or progesterone. I'm just saying. So maybe we pull out one at a time versus just getting this sort of package delivery that might not be, it might be a little overwhelming for me.
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And maybe for you too, not you, but you. Hopefully, know, because I know it's coming up a lot in your feed, but I don't doubt that these clinics are super helpful for the right people, you know, like, and this is the thing. this isn't for sure. Yeah. And so those types of clinics will have functional doctors and nutritionists and naturopaths or whoever it is, chiropractors, whoever is sort of delivering the protocols.
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be super sensible. And I think just that it's just understanding, I guess, the use case for it. When is it appropriate? And when is it potentially, it's not the first thing you go to when you potentially have challenges. Or maybe it is, like maybe for some people getting these peptides are going to help balance things out. So they're then able to address these other foundational pillars. there's no
23:09
I guess there's no way to sort of look at it. But if you're just after a quick fix, knowing that you haven't done the work, then do the work first and spend your money that way before going there. I would probably agree with that too. think sometimes you kind of have to do, put the pillars in place, that's your foundation and then kind of add to it. I don't know, clearly I'm brought this conversation up because there must be some reason that
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they exist and I'm sure there's people that benefit from them and who knows? maybe I would be a person who'd benefit from I don't know. But like the bottom line is that I really like to understand what I'm putting in my body before I put it in. So I like as much information about, I want as much intake and intel on my body, in my body. And I also definitely want to make sure that those pillars are so rooted. I mean,
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People always assume that just because you and I are in the business that we're in, that somehow our pillars are just so perfect and they're not. You know what I mean? We're always adjusting sleep and adjusting protein and adjusting our nutritional balance and adjusting our strength work to where we are and what we need. I think it's important for you guys to just think, put the pillars in place first and then we will continue to unpack the peptide story. Because I think there's a lot to tell. I don't think it's just a quick
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it's not a quick book. I think the book is long and we're still figuring out, we're still writing the story of it. So, we'll continue this conversation. Jess, what are you grateful for this evening? I am very grateful for my Mondays that get to culminate with our discussions. I am truly happy always for you. I'm very grateful for the discussions that we have because I
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I do think that they help. I really think that they help. My goal is to help and service women and I want to have a place where we can kind of talk about this and give people the information that they actually need. Not more than they need, but just what they need so they can use it. And I'm grateful. I'm grateful. had really exceptional weather. It's been very, very rainy and kind of just wintery gloomy and it was like 79 out today. So I was feeling all of that.
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vitamin D in the body and it's me feel better. So I'm grateful for that. How about you? That is, I love that. Do you know, I was chatting to my friend, Nikki, this morning and we were talking about how for whatever reason, sometimes when you get into that scarcity mindset, you know, might be food, it might be money or whatever, you do the exact opposite of what you should do. I was, we were laughing at ourselves because both of us felt like we were in pavo.
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i.e. poverty. And so we went and spent money and we're like crazy. I was grateful to have that shared experience that I was thinking, oh God, this is terrible behavior. But then to know that this is just a normal sort of reaction with the people around me, like, cool, I'm not the only one. You know what? That's like a neuroscience hack, they call it. When you get into that swirl, when you get into that, you know,
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abundant, scarce mindset, even the gratitude practice. The gratitude practice has always been like, why do you do all the time? Very simply, this is not a Pollyanna, like the world is so perfect in rainbows. This is literally to me the fastest way to change the energetics of what's going on in my body. Like, whoop, it just changes that. And what you just did when you went into that kind of like scarce feeling, whatever is scarce for you, you you kind of dove in and went the other side. You're like, well,
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I'm going to go turn left and just dive right in and buy a few things and just kind of buy those yellow G-Star pants. What would you buy? was the thing you spent money on? Yellow denim G-Star trousers. They're awesome. Can't wait for them to arrive. Can't wait, but not as cute as our matching outfits for our podcast. Never a shoe. No. Well, I can't wait to see them. Will you please post something with your yellow jeans on? I will. I will. All right,
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Bye, everybody.
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